Ruihua DONG 董瑞华

Associate Professor, PI, Ph.D
School of Rehabilitation Sciences and Engineering
University of Health and Rehabilitation Sciences (康复大学)

Email: dongruihua@uhrs.edu.cn
[微信] [Lab Website] [Google Scholar] [ResearchGate] [ORCID]

Education | Publications | Patents | Presentations | Awards

Bio

 Ruihua Dong, Ph.D. is a High-Level Assistant Professor and independent Principal Investigator at the University of Health and Rehabilitation Sciences, Deputy Director of Research at Qingdao Central Hospital, Master’s Supervisor, and Postdoctoral Co-supervisor. He was selected for the 2025 Hong Kong Scholars Program by the Ministry of Human Resources and Social Security of China and was awarded the 2023 Taishan Young Scholar of Shandong Province. He also serves as the Director of the Qingdao Innovation Center for Visualized Diagnosis, Therapy, and Rehabilitation Technologies (2024). Dr. Dong received his Ph.D. from Harbin Institute of Technology and completed his postdoctoral training at The Chinese University of Hong Kong, Shenzhen and City University of Hong Kong. His research focuses on aggregation-induced emission (AIE) nanomaterials and their biomedical applications, with extensive expertise in nano-antibacterial materials, flexible bioelectronics, and personalized theranostics. To date, Dr. Dong has published over 40 SCI-indexed papers, including 20 first- or corresponding-author papers in leading journals such as Advanced Materials, Advanced Functional Materials, ACS Nano, Aggregate, and Small. His work has received more than 2,500 citations, with an H-index of 28. He has filed over 30 Chinese invention patents, of which 27 have been granted. As Principal Investigator, he has led multiple competitive research grants, including the National Natural Science Foundation of China (Youth Program), the China Postdoctoral Science Foundation Special Funding Program, the General Program of the China Postdoctoral Science Foundation, the Natural Science Foundation of Shandong Province, and the Open Research Program of Guangdong Provincial Key Laboratory. His research group is dedicated to the emerging field of Nano-Rehabilitation Medicine, integrating nanobiomaterials and flexible bioelectronic devices to develop innovative strategies for tissue repair and regeneration, image-guided theranostics, and flexible biomedical electronics.
董瑞华，康复大学高层次助理教授/独立PI，青岛中心医院科研副主任，硕士生导师，博士后合作导师，2025国家人社部香江学者，2023山东省泰山学者青年专家，2024青岛市可视化诊疗与康复技术创新中心负责人。哈尔滨工业大学博士，香港中文大学（深圳）和香港城市大学博士后，主要从事AIE纳米材料及其生物医学应用的研究工作，在纳米抗菌材料、柔性电子器件及个性化诊疗等方面积累了丰富的经验，相关研究成果发表SCI论文40余篇，其中以第一或通讯作者在Adv Mater, Adv Funct Mater, ACS Nano, Aggregate, Small等权威期刊发表论文17篇，论文引用2500余次，H指数28，申请国家发明专利30余项，获得授权发明专利27项。作为负责人主持国家自然科学基金青年基金、中国博士后特别资助站中项目、中国博士后面上项目，山东省自然科学基金、广东省重点实验室面上项目，作为项目骨干参与军委科技委国防科技创新特区重点项目2项（排名第2，累计经费1000万），受邀担任Nature Communications, Nano Energy, Environmental Science & Technology, Journal of Hazardous Materials等国际期刊独立审稿人，相关研究工作受到Materials Views China、Deep Tech等国内外媒体采访报道。 课题组以“纳米康复医学”为研究方向，以纳米生物材料和柔性电子器件为基础，开展组织修复再生、可视化诊疗和柔性生物电子等应用研究工作。与唐本忠院士课题组、蒋兴宇教授课题组、刘绍琴教授课题组建立了长期合作，为实验室建设和发展提供了技术和平台基础，欢迎跨学科交叉合作。 课题组网站：https://www.x-mol.com/groups/dongruihua !

News

Education and Employment

Research Experience

Publications

2026 update:

    [40] Shengyan Yin, Yingcai Hu, Guangxia Lv, Jiuqiang Ding, Ruihua Dong*, "A Multifunctional Charged Molecule-Embedded Nanofibrous Dressing with Dual Light/Dark Activity for Tumor-Antibacterial Synergistic Therapy", Chem Eng J 2026, 534, 175308. (IF=13.2)

    [39] Xiaoyan Liu, Ruihua Dong, Chen Hang, Chwee Teck Lim*, Xingyu Jiang*, "Brain Extracellular Matrix-Based Electronic Brain Biochip", ACS Nano 2026, 20, 9482.(IF=16.0)

    [38] Zijuan Meng#, Xiaohua Ji#, Shengyan Yin, Zhen Zhang*, Ruihua Dong*, Zheng Zhao*, Ben Zhong Tang*, "Preclinical Studies on the Photothermal Therapy of AIEgens: Across Tumor Types", Small 2025, 21, e09080.(IF=12.1)

    [37] Haifei Wen#, Ziwei Deng, Ruihua Dong#, Zicong Zhang, Ximing Chen, Gian Albert Alfani, Wenjin Wang, Zijie Qiu, Parvej Alam*, Zheng Zhao*, Ben Zhong Tang*, "Sulfur-π Interaction: A New Strategy for Designing NIR-II AIE Photosensitizers for Wound Healing", Adv. Funct. Mater. 2025, 35, 2508015. (IF=19.0)

    [36] Shuai Yuan, Peng Zhang, Feng Zhang, Shiqiang Yan, Ruihua Dong, Chengjun Wu, Jiu Deng*, "Profiling signaling mediators for cell-cell interactions and communications with microfluidics-based single-cell analysis tools", iScience. 2025, 28, 111663. (IF=4.6)

    [35] Mian Chen#, Ruihua Dong#, Jiayi Song, Jie Qi, Jiangjiang Zhang, Zheng Zhao*, Wentian Zhang, Ying Li*, Ben Zhong Tang*, "Fast and stable antibacterial coating of photosensitive aggregation-induced emission luminogens for disinfection on medical devices", Adv. Healthc. Mater. 2024, 13, 2303967. (IF=10.0)

    [34] Ruihua Dong, Lulu Wang, Zebin Li, Jincheng Jiao, Yan Wu, Zhuowei Feng, Xufang Wang, Minglong Chen, Chang Cui, Yi Lu, Xingyu Jiang*, "Stretchable, self-rolled, microfluidic electronics enable conformable neural interfaces of brain and vagus neuromodulation", ACS Nano 2024, 18, 1702. (IF=17.1)

    [33] Ruihua Dong, Mian Chen, Yuexiao Jia, Hao Tang, Ziyin Xiong, Yunze Long*, Xingyu Jiang*, “An in situ dressing material containing a multi-armed antibiotic for healing irregular wounds”, Aggregate 2024, e493. (IF=18.8)

    [32] Jinhui Jiang, Fulong Ma, Ruihua Dong, Siwei Zhang, Zicong Zhang, Haozhe Tan, Xumin Cai, Zijie Qiu, Yu Xiong*, Wei Han*, Zheng Zhao*, Ben Zhong Tang*, J. Am. Chem. Soc. 2023, 145, 27282. (IF=15.0)

    [31] Yan Wu, Jinhao Cheng, Jie Qi, Chen Hang, Ruihua Dong, Boon Chuan Low, Hanry Yu, Xingyu Jiang* Nat. Commun. 2024, 15, 4047. (16.6)

    [30] Yuexiao Jia, Wenwen Chen, Rongbing Tang, Jiangjiang Zhang, Xiaoyan Liu, Ruihua Dong, Fupin Hu and Xingyu Jiang*, Cell Host & Microbe 2023, 31, 1101. (IF=30.3)


Prior to UHRS:

    [29] Ruihua Dong, Ying Li, Mian Chen, Peihong Xiao, Kun Zhou, Zheng Zhao*, Benzhong Tang*, "In situ electrospinning of aggregation-induced emission nanofibrous dressing for wound healing", Small Methods 2022, 2101247. (IF=15.367, Quote:36, Highly Cited Paper)

    [28] Dou Wang#, Ruihua Dong#, Xuedong Wang, Xingyu Jiang*, "Flexible electronic catheter for capture and elimination of circulating tumor cells", ACS Nano 2022, 16(4), 5274. (IF=18.027, Quote:10)

    [27] Ruihua Dong, Lulu Wang, Chen Hang, Zhen Chen, Xiaoyan Liu, Leni Zhong, Jie Qi, Yuqing Huang, Shaoqin Liu*, Liping Wang*, Yi Lu*, Xingyu Jiang*, "Printed stretchable liquid metal electrode arrays for in vivo neural recording", Small 2021, 17, 2006612. (IF=15.153, Quote:36, Top Downloaded Article)

    [26] Ruihua Dong, Xiaoyan Liu, Shiyu Cheng, Lixue Tang, Mian Chen, Leni Zhong, Zhen Chen, Shaoqin Liu*, Xingyu Jiang*, "Highly stretchable metal-polymer conductor electrode array for electrophysiology", Adv. Healthc. Mater. 2020, 10, 2000641. (IF=11.092, Quote:16)

    [25] Ruihua Dong, Yong Liu, Lei Mou, Jinqi Deng, Xingyu Jiang*, "Microfluidics-based biomaterials and biodevices", Adv. Mater. 2019, 31, 1805033. (IF=32.086, Quote:99)

    [24] Ruihua Dong, Yuexiao Jia, Chongchong Qin, Lu Zhan, Xu Yan, Lin Cui, Yu Zhou, Xingyu Jiang and Yunze Long*, "In situ deposition of a personalized nanofibrous dressing via a handy electrospinning device for skin wound care", Nanoscale 2016, 8, 3482. (IF=8.037, Quote:160)

    [23] Ruihua Dong, Chongchong Qin, Xuan Qiu, Xu Yan, Miao Yu, Lin Cui, Yu Zhou, Hongdi Zhang, Xingyu Jiang, Yunze Long*, "In situ precision electrospinning as an effective delivery technique for cyanoacrylate medical glue with high efficiency and low toxicity", Nanoscale 2015, 7, 19648. (IF=8.037, Quote:50)

    [22] Fuyan Lv#, Ruihua Dong#, Zhaojian Li, Chongchong Qin, Xu Yan, Xiaoxiao He, Yu Zhou, Shiying Yan, Yunze Long*, "In situ precise electrospinning of medical glue fibers as nonsuture dural repair with high sealing capability and flexibility", Int. J. Nanomedicine 2016, 11, 4213. (IF=7.033, Quote:20)

    [21] Miao Yu#, Ruihua Dong#, Xu Yan, Guifeng Yu, Minghao You, Xin Ning, Yunze Long*, "Recent advances in needleless electrospinning of ultrathin fibers: from academia to industrial production", Macromol. Mater. Eng. 2017, 302, 1700002. (IF=4.402, Quote:121)

    [20] Yifan Wu, Jiangao Li, Zipeng Shen, Deliang Wang, Ruihua Dong, Jiangjiang Zhang, Yinzhen Pan, Ying Li, Dong Wang, Ben Zhong Tang*, Angewandte Chemie 2022, 134, e202212386. (IF=16.823)

    [19] Yuexiao Jia, Jiangjiang Zhang, Yingcan Zhao, Ruihua Dong, Hui Wang, and Xingyu Jiang*, Chem. Commun. 2022, 58, 10544. (IF=6.065)

    [18] Li Ding, Chen Hang, Shuaijian Yang, Jie Qi, Ruihua Dong, Yan Zhang, Hansong Sun, and Xingyu Jiang*, Nano Letters 2022, 22, 4482. (IF=12.262)

    [17] Mian Chen, Jiangjiang Zhang, Jie Qi, Ruihua Dong, Hongmei Liu, Decheng Wu, Huawu Shao, and Xingyu Jiang*, ACS Nano 2022, 16, 7732. (IF=18.027)

    [16] Shuting Cheng, Mian Chen, Kun Wang, Qingqing Liu, Yi Cheng, Ruihua Dong, Kewen Huang, Hao Yuan, Jun Jiang, Wenjuan Li, Junliang Li, Ce Tu, Jian Liu, Xingyu Jiang*, Yue Qi*, and Zhongfan Liu*, J. Mater. Chem. A 2022, 10, 12125. (IF=14.511)

    [15] Chen Hang, Li Ding, Shiyu Cheng, Ruihua Dong, Jie Qi, Xiaoyan Liu, Qian Liu, Yan Zhang and Xingyu Jiang*, Adv. Mater. 2021, 2101447. (IF=32.086)

    [14] Mian Chen, Ruihua Dong, Jiangjiang Zhang, Hao Tang, Qizhen Li, Huawu Shao and Xingyu Jiang*, ACS Appl. Mater. Interfaces 2021, 10, 29398. (IF=10.383)

    [13] Lei Mou, Jie Qi, Lixue Tang, Ruihua Dong, Yuan Gao* and Xingyu Jiang*, Small 2020, 16, 2005336. (IF=15.153)

    [12] Shiyu Cheng, Chen Hang, Li Ding, Liujun Jia, Lixue Tang, Lei Mou, Jie Qi, Ruihua Dong, Wenfu Zheng, Yan Zhang, Xingyu Jiang*, Matter 2020, 3, 1664. (IF=19.967)

    [11] Xiaohui Zhao, Yuexiao Jia, Ruihua Dong, Jinqi Deng, Hao Tang, Fupin Hu, Shaoqin Liu, Xingyu Jiang*, Chem. Commun. 2020, 56, 10918. (IF=6.065)

    [10] Mian Chen, Zhou Long, Ruihua Dong, Le Wang, Jiangjiang Zhang, Sixiang Li, Xiaohui Zhao, Xiandeng Hou, Huawu Shao, Xingyu Jiang*, Small 2020, 16, 1906240. (IF=15.153)

    [9] Lei Mou, Ruihua Dong, Binfeng Hu, Zulan Li, JiangJiang Zhang, Xingyu Jiang*, Lab Chip 2019, 19, 2750. (IF=7.517)

    [8] Jun Li, Chunlin Sun, Pengrong An, Xiaoyan Liu, Ruihua Dong, Jinghong Sun, Xingyu Zhang, Yanbo Xie, Chuanguang Qin, Wenfu Zheng, Haoli Zhang, Xingyu Jiang*, J. Am. Chem. Soc. 2019, 141, 8816. (IF=16.383)

    [7] Xiaohui Zhao, Yuexiao Jia, Juanjuan Li, Ruihua Dong, Jiangjiang Zhang, Xingyu Jiang*, ACS Appl. Mater. Interfaces 2018, 10, 29398. (IF=10.383)

    [6] Shicong Xu, Chongchong Qin, Miao Yu, Ruihua Dong, Xu Yan, Hui Zhao, Wenpeng Han, Hongdi Zhang and Yunze Long*, Nanoscale 2015, 7, 12351. (IF=8.307)

    [5] Xu Yan, Miao Yu, Lihua Zhang, Xiansheng Jia, Jintao Li, Xiaopeng Duan, Chongchong Qin, Ruihua Dong and Yunze Long*, Nanoscale 2016, 8, 209. (IF=8.307)

    [4] Hongwei He, Bin Zhang, Xu Yan, Ruihua Dong, Xiansheng Jia, Guifeng Yu, Xin Ning, Linhua Xia and Yunze Long*, RSC Adv. 2016, 6, 106945. (IF=4.036)

    [3] Chongchong Qin, Xiaopeng Duan, Le Wang, Lihua Zhang, Miao Yu, Ruihua Dong, Xu Yan, Hongwei He and Yunze Long*, Nanoscale 2015, 7, 16611. (IF=8.307)

    [2] Xu Yan, Miao Yu, Wenpeng Han, Minghao You, Juncheng Zhang, Ruihua Dong, Hongdi Zhang and Yunze Long*, Chin. Phys. B 2016, 25, 7, 078106. (IF=1.652)

    [1] Hongwei He, Le Wang, Xu Yan, Lihua Zhang, Miao Yu, Guifeng Yu, Ruihua Dong, Linhua Xia, Seeram Ramakrishna* and Yunze Long*, RSC Adv. 2016, 6, 29423. (IF=4.036)


Patents

Issued China patent:

    [1] 一种磁纺装置及使用该装置制备微纳米纤维的方法，龙云泽，董瑞华，李金涛，贾宪生，闫旭，于桂凤，魏代善，管殿柱，授权发明专利，CN104878456B，20170222.

    [2] 一种熔体磁纺丝装置及利用该装置制备微纳米纤维的方法，龙云泽，董瑞华，闫旭，段晓鹏，犹明浩，王乐，张丽华，魏代善，管殿柱，授权发明专利，CN104878455B，20170315.

    [3] 一种大规模磁纺设备及用该设备制备微纳米纤维的方法，龙云泽，董瑞华，闫旭，李金涛，魏代善，于桂凤，贺晓晓，犹明浩，管殿柱，授权发明专利，CN104878461B，20170503.

    [4] 一种纳米纤维抗菌敷料原位制备方法，于淼，董瑞华，龙云泽，闫旭，于桂凤，韩文鹏，张红娣，授权发明专利，CN104667338B，20170808.

    [5] 一种便携式静电纺丝设备及其使用方法，于淼，龙云泽，董瑞华，闫旭，秦崇崇，韩文鹏，授权发明专利，CN104790049B，20160907.

    [6] 一种微波加热熔体静电纺丝装置，龙云泽，黄渊源，董瑞华，闫旭，韩文鹏，张君诚，段晓鹏，秦崇崇，林大鹏，授权发明专利，CN104131358B，20170609.

    [7] 一种磁纺制备导电聚合物微纳米纤维的方法，龙云泽，于桂凤，董瑞华，闫旭，李金涛，贾宪生，贺晓晓，魏代善，管殿柱，授权发明专利，CN104911719B，20170707.

    [8] 一种磁纺制备石墨烯/聚合物有序微纳米复合纤维的方法，韩文鹏，龙云泽，董瑞华，闫旭，贾宪生，李金涛，赵惠，贺晓晓，魏代善，管殿柱，授权发明专利，CN104862799B，20170118.

    [9] 一种大规模制备微纳米纤维的静电纺丝装置，于淼，龙云泽，董瑞华，秦崇崇，授权发明专利，CN105970313B，20180824.

    [10] 一种利用气压恒定供液的静电纺丝装置，于淼，龙云泽，董瑞华，秦崇崇，授权发明专利，CN105951190B，20180824.

    [11] 一种气流辅助线性齿电极静电纺丝装置，于淼，龙云泽，董瑞华，秦崇崇，授权发明专利，CN105970314，20180824.

    [12] 一种消除PM2.5颗粒物的静电喷雾路灯装置，于淼，闫旭，龙云泽，董瑞华，盛琛皓，韩文鹏，授权发明专利，CN104776384B，20170412.

    [13] 一种消除汽车尾气中PM2.5颗粒物的装置及其使用方法，于淼，闫旭，龙云泽，董瑞华，盛琛皓，韩文鹏，授权发明专利，CN104912627B，20180511.

    [14] 一种低温原位静电纺丝装置，龙云泽，闫旭，韩文鹏，秦崇崇，董瑞华，张红娣，张君诚，于经学，林大鹏，盛琛皓，授权发明专利，CN104313707B，20160824.

    [15] 一种交叉纳米纤维P-N异质结阵列的制备方法，龙云泽，陈帅，盛琛皓，韩文鹏，董瑞华，张红娣，授权发明专利，CN103943778B，20160817.

    [16] 一种静电喷雾消除可入肺颗粒物的方法，龙云泽，闫旭，韩文鹏，秦崇崇，董瑞华，张红娣，张君诚，林大鹏，盛琛皓，赵惠，张保生，授权发明专利，CN104259002B，20161012.

    [17] 一种无溶剂静电纺丝制备聚氨酯微纳米纤维的方法，龙云泽，何宏伟，林大鹏，闫旭，韩文鹏，王乐，张丽华，董瑞华，授权发明专利，CN104532367B，20160824.

    [18] 一种规模化无溶剂电纺制备光固化材料微纳米纤维的方法，龙云泽，何宏伟，张丽华，王乐，段晓鹏，董瑞华，秦崇崇，赵惠，夏临华，授权发明专利，CN105220244A，20160106.

    [19] 一种基于UV固化的无溶剂静电纺丝装置，龙云泽，何宏伟，王乐，张丽华，段晓鹏，董瑞华，秦崇崇，赵惠，夏临华，授权发明专利，CN105088367B，20171222.

    [20] 一种力敏可拉伸电纺图案化导电纳米纤维膜及其制备方法，龙云泽，于桂凤，闫旭，贺晓晓，韩文鹏，董瑞华，贾宪生，李金涛，犹明浩，授权发明专利，CN104894750B，20170503.

    [21] 一种电容式超薄柔性应力传感器及其制备方法，闫旭，龙云泽，于桂凤，贺晓晓，王乐，董瑞华，贾宪生，李金涛，授权发明专利，CN104897316B，20170926.

    [22] 一种氯化钴湿敏电纺微纳米纤维膜及其制备方法和应用，闫旭，龙云泽，犹明浩，于桂凤，贺晓晓，贾宪生，董瑞华，张红娣，授权发明专利，CN105568557B，20190118.

    [23] 颅内伤口愈合监测装置、其制备方法及应用，蒋兴宇，董瑞华，奚磊，秦伟，授权发明专利，CN109222905A，20190118.

    [24] 一种负载AIE荧光纳米纤维敷料制备方法与应用，蒋兴宇，董瑞华，授权发明专利，CN110787316A，20200214.




Substantive examination:

    [25] 一种壳聚糖纳米纤维及其规模化电纺制备方法和应用，于淼，龙云泽，董瑞华，闫旭，发明专利申请，CN106693030A，20170524

    [26]一种海藻酸钠纳米纤维及其规模化电纺制备方法和应用，于淼，龙云泽，董瑞华，闫旭，发明专利申请，CN106480517A，20170308.

    [27] 一种柔性可拉伸神经电极及其制备方法和应用，蒋兴宇，董瑞华，刘晓艳，唐立雪，发明专利申请，CN110251125A，20190920.

    [28] 一种液态金属微电极阵列及其制备方法，蒋兴宇，董瑞华，发明专利申请，CN111920404A，20201113.

    [29] 一种软硬可调的植入式神经电极及其制备方法，蒋兴宇，董瑞华，发明专利申请，CN202011414621.6，20200703

    [30] 一种液态金属光遗传神经电极及其制备方法，蒋兴宇，董瑞华，发明专利申请，CN113476749A，20210115

    [31] 一种自卷曲液态金属外周神经电极及其制备方法，蒋兴宇，董瑞华，李泽彬，发明专利申请，20220321.

    [32] 一种液态金属微丝神经电极及其制备方法，蒋兴宇，董瑞华，文天昀，发明专利申请，20220322.


Presentations
  • Ruihua Dong, Zheng Zhao*, Benzhong Tang*, Aggregate Science 20th Anniversary of AIE Research, 2021, Guangzhou
  • Ruihua Dong, Xingyu Jiang*, 第八届国际微流控学学术论坛，2021，Shenzhen
  • Ruihua Dong, Xingyu Jiang*, 中国神经科学学会神经科学研究技术分会2019年学术年会, 2019, Shenzhen
  • Ruihua Dong, Xingyu Jiang*, AsiaNANO2018, Oct. 2018, Qingdao. Oral
  • Ruihua Dong, Xingyu Jiang*, 2018 Conference on Biomedical Engineering, Sep. 2018, Shenzhen. Oral
  • Ruihua Dong, Xingyu Jiang*, 7th ChinaNano, Aug. 2017, Beijing. Poster
  • Ruihua Dong, Yunze Long*, 4th National Conference on Electrospinning, Dec. 2016, Beijing. Best Poster
  • Ruihua Dong, Yunze Long*, 3rd National Conference on Electrospinning, Sep. 2015, Qingdao. Best Poster

Awards
  • 2023, Qingdao AIE Technology Innovation Center
  • 2023, Shandong Province Young Taishan Scholar
  • 2022, National Natural Science Foundation of China
  • 2022, China Postdoctoral Science special Foundation
  • 2021, China Postdoctoral Science Foundation
  • 2016, Second Prize of Innovation Achievement of Shandong Province
  • 2016, Excellent Student of Shandong Province
  • 2016, Academic Star of Qingdao University
  • 2016, National Scholarship
  • 2013, Outstanding Graduates of Qingdao University